Table 1 Demographic and metabolic characteristics of mother-infant dyads from cohorts I and II.

Values represent means and SD.

Cohort ICohort II
Mothern = 34n = 109
Age (years)29.1 ± 5.132.8 ± 6.2
Prepregnancy BMI
(kg/m2)
27.3 ± 7.123.5 ± 3.8
Gestational weight
gain (kg)*
12.0 ± 7.412.1 ± 4.7
Infant
Birthn = 34n = 109
Gender (female/male)15/1960/49
Gestational age
(weeks)
39.6 ± 1.239.6 ± 1.1
Weight (kg)3.53 ± 0.483.35 ± 0.44
Length (cm)51.6 ± 2.350.1 ± 2.2
Weight-for-length
z score
−0.59 ± 1.2−0.20 ± 1.15
1 monthn = 34n = 109
Weight (kg)4.67 ± 0.714.23 ± 0.57
Length (cm)55.8 ± 2.154.5 ± 2.3
Weight-for-length
z score
−0.36 ± 1.04−0.50 ± 1.17
12 monthsn = 107
Weight (kg)9.46 ± 1.04
Length (cm)74.8 ± 2.9
Weight-for-length
z score
0.18 ± 0.87
Breast milk
metabolites
n = 34n = 109
SAM (nM)1469 ± 4362034 ± 649
SAH (nM)216 ± 81327 ± 184
Methionine (μM)4.39 ± 2.696.74 ± 12.36
Cystathionine (nM)44.9 ± 34.3129.6 ± 75.7
Betaine (μM)3.12 ± 2.655.33 ± 6.13
Choline (μM)97 ± 49165 ± 115

*n = 32 for gestational weight gain data in cohort I.