Table 1 Demographic, pathological, and clinical characteristics of patients treated in cohorts 1 to 3.

CharacteristicsPart 1
Cohort 1
n = 6
Cohort 2
n = 7
Cohort 3
n = 3
Total
n = 16
Median age, years (range)61 (49–73)58 (42–74)58 (46–78)58 (42–78)
Male (%), female (%)2 (33), 4 (67)2 (29), 5 (71)1 (33), 2 (67)5 (31), 11 (69)
Tumor type, n (%)
  Melanoma4105 (31)
  Leiomyosarcoma0213 (19)
  Breast carcinoma1102 (13)
  Other (adenoid cystic
carcinoma, colorectal
cancer, endometrial
neuroendocrine carcinoma,
head and neck cancer,
ovarian cancer, and
mesothelioma; n = 1 per type)
1326 (38)
Previous lines of oncology
therapy, n (%)
  00000
  11102 (13)
  2 or more56314 (88)
Previous radiotherapy, n (%)46111 (69)
Site of target (injected) lesion,
n (%)
  Skin/subcutaneous nodule2406 (38)
  Lymph node2204 (25)
  Soft tissue2024 (25)
  Liver0112 (13)