Table 2 Clinical and laboratory findings in subgroups of pediatric and adult patients with COVID-19.

Data are mean ± SD. ANC, absolute neutrophil count; Gp, group; WBC, white blood cell; NS, not significant.

Group 1Group 2Group 3Group 4Group 5P value*
Age <24 (no
mechanical
ventilation)
(n = 41)
MIS-C (n = 20)Adult (no
mechanical
ventilation)
(n = 33)
Adult (mechanical
ventilation or
death) (n = 27)
Age <24
(mechanical
ventilation or
death) (n = 4)
Age (years)14.90 ± 5.619.15 ± 5.2859.42 ± 14.8963.04 ± 10.0518.25 ± 3.30<0.0001
Days since onset of
symptoms
4.51 ± 4.57 (n = 33)4.06 ± 1.47 (n = 18)5.00 ± 3.04 (n = 31)4.70 ± 2.91 (n = 23)3.75 ± 2.75 (n = 4)NS
BMI30.45 ± 15.48 (n = 36)19.04 ± 5.81 (n = 19)29.61 ± 5.77 (n = 31)29.99 ± 5.52 (n = 26)28.00 ± 9.93 (n = 4)<0.01 (Gp 2 versus 1,
3, and 4) and <0.05
(Gp 2 versus 5)
LOS4.84 ± 5.36 (n = 38)8.10 ± 4.05 (n = 20)7.88 ± 6.84 (n = 33)37.50 ± 19.60 (n = 10)21.00 ± 9.90 (n = 2)<0.0001 (Gp 4
versus 1, 2, and 3)
Mortality (n)000172<0.0001 (Gp 4 versus 1, 2, and 3)
WBC (×10−3 cells/μl)9.89 ± 6.639.39 ± 3.787.15 ± 4.578.29 ± 2.6211.15 ± 4.01NS
Hemoglobin (g/dl)13.22 ± 2.8611.23 ± 1.8312.65 ± 2.0212.89 ± 2.3212.33 ± 1.24NS
Platelets
(×10−3 cells/μl)
265.29 ± 144.25174.95 ± 98.23206.62 ± 80.29214.85 ± 823.28181.25.00 ± 538.84NS
ANC (cells/μl)6878.05 ± 5664.747750.00 ± 3623.535339.39 ± 4224.776533.33 ± 2344.558900.00 ± 2892.52NS
ALC (cells/μl)2092.68 ± 1443.501105.00 ± 592.471069.70 ± 470.691129.63 ± 685.461450.00 ± 925.56<0.01 (Gp 1 versus
2, 3, and 4)
CRP (mg/dl)4.56 ± 7.11 (n = 34)18.80 ± 13.57
(n = 19)
12.83 ± 7.75 (n = 20)19.50 ± 12.83
(n = 17)
18.95 ± 11.37 (n = 4)<0.0001 (Gp 1 versus
2 and 4) and <−0.05
(Gp 1 versus 3)
CRP (peak) (mg/dl)9.66 ± 10.67 (n = 31)24.49 ± 10.95
(n = 18)
14.10 ± 8.90 (n = 25)31.06 ± 17.94
(n = 23)
24.13 ± 9.98 (n = 4)<0.0001 (Gp 1 and 3
versus 4) and <0.01
(Gp 1 versus 2)
Ferritin (peak)
(ng/ml)
969.52 ± 1155.33
(n = 27)
1893.16 ± 3144.32
(n = 19)
1276.11 ± 1551.25
(n = 9)
4158.47 ± 5192.46
(n = 17)
1257.25 ± 1076.43
(n = 4)
NS
LDH (peak) (U/liter)415.78 ± 255.56
(n = 27)
509.74 ± 434.86
(n = 19)
460.00 ± 165.62
(n = 26)
770.88 ± 553.94
(n = 24)
797.25 ± 233.62
(n = 4)
<0.01 (Gp 1 versus
4) and <0.05 (Gp 3
versus 4)
Troponin (peak)
(ng/ml)
0.01 ± 0.005 (n = 25)0.09 ± 0.16 (n = 18)0.12 ± 0.56 (n = 30)0.07 ± 0.10 (n = 26)0.10 ± 0.12 (n = 4)NS
CPK (peak) (U/liter)645.65 ± 1150.71
(n = 20)
517.47 ± 438.42
(n = 17)
537.93 ± 675.00
(n = 29)
757.29 ± 1307.40
(n = 24)
1088.25 ± 690.81
(n = 4)
NS
D-dimer (peak)
(μg/ml)
1.43 ± 1.52 (n = 25)11.14 ± 7.00 (n = 18)2.58 ± 1.72 (n = 17)12.57 ± 9.46 (n = 17)9.30 ± 5.96 (n = 4)<0.001 (Gp1 versus
2; 2 versus 3), <0.01
(Gp 1 versus 4), and
<0.05 (Gp 3 versus 4)

*Groups 1 to 4 were compared by ANOVA with Tukey’s multiple comparison.

†Laboratory values are from the time of admission unless indicated as peak.