Table 2 Clinical and laboratory findings in subgroups of pediatric and adult patients with COVID-19

Group 1Group 2Group 3Group 4Group 5p-value^
Age <24 (no mechanical ventilation)
(n=41)
MIS-C
(n=20)
Adult (no mechanical ventilation)
(n=33)
Adult (mechanical ventilation or death)
(n=27)
Age < 24 (mechanical ventilation or death)
(n=4)
Age (years)14.90 ± 5.619.15 ± 5.2859.42 ± 14.8963.04 ± 10.0518.25 ± 3.30<0.0001
Days since onset of symptoms4.51 ± 4.57
(n=33)
4.06± 1.47
(n=18)
5.00 ± 3.04
(n=31)
4.70 ± 2.91
(n=23)
3.75 ± 2.75
(n=4)
NS
Body mass index30.45 ± 15.48
(n=36)
19.04 ± 5.81
(n=19)
29.61 ± 5.77
(n=31)
29.99 ± 5.52
(n=26)
28.00 ± 9.93
(n=4)
<0.01 (Gp 2 vs 1, 3, 4)
< 0.05 (Gp 2 vs 5)
Length of stay^^^4.84 ± 5.36
(n=38)
8.10 ± 4.05
(n=20)
7.88 ± 6.84
(n=33)
37.50 ± 19.60
(n=10)
21 0.00 ± 9.90
(n=2)
<0.0001 (Gp 4 vs 1, 2, 3)
Mortality (n)000172<0.0001 (Gp 4 vs 1, 2, 3)
WBC (×10−3 cells/μl)9.89 ± 6.639.39 ± 3.787.15 ± 4.578.29 ± 2.6211.15 ± 4.01NS
Hemoglobin (g/dL)13.22 ± 2.8611.23 ± 1.8312.65 ± 2.0212.89 ± 2.3212.33 ± 1.24NS
Platelets (×10−3 cells/μl)265.29 ± 144.25174.95 ±98.23206.62 ± 80.29214.85 ± 823.28181.25.00 ± 538.84NS
ANC (cells/μl)6878.05 ± 5664.747750.00 ± 3623.535339.39 ± 4224.776533.33 ± 2344.558900.00 ±
2892.52
NS
ALC (cells/μl)2092.68 ± 1443.501105.00 ±
592.47
1069.70 ±
470.69
1129.63 ±
685.46
1450.00 ±
925.56
<0.01 (Gp 1 vs 2, 3 and 4)
CRP (mg/dL)4.56 ± 7.11
(n=34)
18.80 ± 13.57
(n=19)
12.83 ± 7.75
(n=20)
19.50 ± 12.83
(n=17)
18.95 ± 11.37
(n=4)
< 0.0001 (Gp 1 vs 2 and 4);
<-0.05 (Gp 1 vs 3)
CRP (peak)
(mg/dL)
9.66 ± 10.67
(n=31)
24.49 ±10.95
(n=18)
14.10 ± 8.90
(n=25)
31.06 ± 17.94
(n=23)
24.13 ± 9.98
(n=4)
< 0.0001 (Gp 1 and 3 vs 4);
< 0.01 (Gp 1 vs 2)
Ferritin (peak) (ng/mL)969.52 ±
1155.33
(n=27)
1893.16± 3144.32
(n=19)
1276.11 ± 1551.25
(n=9)
4158.47 ± 5192.46
(n=17)
1257.25 ±
1076.43
(n=4)
NS
LDH (peak)
(U/L)
415.78 ±
255.56
(n=27)
509.74 ±
434.86
(n=19)
460.00 ±
165.62
(n=26)
770.88 ±
553.94
(n=24)
797.25 ±
233.62
(n=4)
< 0.01(Gp 1 vs 4);
< 0.05 (Gp 3 vs 4)
Troponin (peak) (ng/mL)0.01± 0.005
(n=25)
0.09 ± 0.16
(n=18)
0.12 ± 0.56
(n=30)
0.07 ± 0.10
(n=26)
0.10 ± 0.12
(n=4)
NS
CPK (peak)
(U/L)
645.65 ± 1150.71 (n=20)517.47 ± 438.42
(n=17)
537.93 ± 675.00
(n=29)
757.29 ± 1307.40
(n=24)
1088.25 ± 690.81
(n=4)
NS
D-dimer (peak) (μg/mL)1.43 ± 1.52
(n=25)
11.14 ± 7.00
(n=18
2.58 ± 1.72
(n=17)
12.57± 9.46
(n=17
9.30 ± 5.96
(n=4)
<0.001 (Gp1 vs 2; 2 vs 3);
< 0.01 (Gp 1 vs 4);
< 0.05 (Gp 3 vs 4)

Data are mean ± standard deviation

ALC= absolute lymphocyte count; ANC= absolute neutrophil count

^ Groups 1-4 were compared by ANOVA with Tukey’s multiple comparison

^^Laboratory values are from time of admission unless indicated as peak