Table 3 Safety profile of mTAA T cells for MM.

Safety profile of mTAA T cells for MM..

Adverse events that could be related to infusion
Events at DL1No. of eventsOutcome
Abdominal pain1 (grade I)Recovered without
intervention
Events at DL2No. of eventsOutcome
Thrombocytopenia1 (grade IV)Resolved to baseline
(grade III) without
intervention
Leukopenia1 (grade III), 1 (grade
II), 2 (grade I)
Persistent (>4 weeks)
in 1 patient, who was
also on maintenance
Imid therapy
Anemia1 (grade III), 1 (grade I)Recovered to baseline
(grade I) without
intervention
Leg cramps1 (grade II)Recovered without
intervention
Abdominal pain1 (grade I)Recovered without
intervention
Fatigue1 (grade I)Recovered without
intervention
Diarrhea1 (grade I)Recovered after
empiric oral
antibiotics
Hospitalizations during the DLT period
EventNo. of patientsSuspected etiology
and outcome
Bronchitis1 (grade III)Viral, recovered to
baseline
Dehydration1 (grade III)Anxiety attack,
recovered to baseline
Renal failure1 (grade III)Concomitant use of
lisinopril for ongoing
hypertension,
recovered to baseline