Table 1 HIV-infected individuals selected for retrospective and prospective analysis of immunological status, viremia, and viral suppression.

Patients were classified as positive or negative for the presence of HIV in platelets according to at least two different techniques. Only HIV-infected individuals for whom clinical data were available 18 months before the date of sampling were included in the analysis. The period of viral suppression in months before the date of sampling is indicated. Competent immunological status was defined as >350 CD4+ T cells/μl of blood for two or more consecutive measurements over 1 year including date of sampling for detecting HIV in platelets. Immunological failure was defined as <350 CD4+ T cells/μl blood for two or more consecutive measurements over 1 year including date of sampling for detecting HIV in platelets. Controlled viremia was defined as <1.60 HIV RNA log10 copies/ml of plasma for at least 1 year before sampling. Uncontrolled viremia was defined as >1.60 HIV RNA log10 copies/ml of plasma at the date of sampling or less than 12 months of continuous viral suppression.

Individual numberImmunological statusViremiaMonths suppressed before
sampling
Individuals negative for HIV
in platelets
39CompetentControlled17
32CompetentControlled18
75CompetentControlled31
54CompetentControlled18
52CompetentControlled12
11CompetentControlled18
51CompetentControlled18
16CompetentControlled12
15CompetentControlled13
61CompetentControlled13
66CompetentControlled47
67CompetentControlled31
4CompetentControlled78
56CompetentControlled62
53In failureControlled22
59In failureControlled18
Median months under controlled viremia (CI)18 (15–31)
7In failureUncontrolled<12
60CompetentUncontrolled<12
24CompetentUncontrolled<12
46CompetentUncontrolled<12
Individuals positive for HIV
in platelets
9In failureControlled24
27In failureControlled38
48In failureControlled19
6In failureControlled20
49In failureControlled50
64In failureControlled52
79In failureControlled14
80In failureControlled62
37CompetentControlled13
Median months under controlled viremia (CI)24 (14–52)
74CompetentUncontrolled<12
25CompetentUncontrolled<12
18In failureUncontrolled<12
78In failureUncontrolled<12
40In failureUncontrolled<12
41In failureUncontrolled<12