Table 1 AUC of glucose concentrations after IPGTT.

Data presented as mean ± SEM. The integrated area under the curve of glucose concentrations was calculated during the 120-min IPGTT (mM × min2) at 2.8, 7, 12, and 16 weeks after islet transplant; n = 6 to 8 mice per group. One-way ANOVA analyses comparing effect of integrated glucose response with ratio of islets: HUCPVCs transplanted under the kidney capsule were compared at separate time intervals. Post hoc analyses for significant differences between ratios of islets to HUCPVCs are denoted: a, 1:0 versus 1:10; b, 1:0 versus 1:30; c, 1:0 versus 1:50; d, 1:10 versus 1:30; e, 1:10 versus 1:50; f, 1:30 versus 1:50.

Weeks after transplantIslet:HUCPVC 1:0Islet:HUCPVC 1:10Islet:HUCPVC 1:30Islet:HUCPVC 1:50P ANOVA
2.8 weeks970 ± 8430 ± 20457 ± 9457 ± 23<0.0001a,b,c
7 weeks902 ± 171672 ± 35473 ± 15691 ± 530.02b
12 weeks1111 ± 1231218 ± 40418 ± 34441 ± 30<0.0001b,c,d,e
16 weeks1089 ± 601045 ± 58544 ± 29721 ± 19<0.0001b,c,d,e,f