Table 1 Baseline demographics and disease characteristics.

Data are means (SD) unless stated otherwise. Pairwise comparisons between treatments and placebo were not significant (P > 0.05), unless otherwise indicated. F, female; LOAD, Liverpool Osteoarthritis in Dogs; M, male.

Placebo
(n = 43)
LYA
(n = 39)
LYB
(n = 42)
Carprofen
(n = 39)
Total
(N = 163)
Age, year9.8 (2.8)9.2 (2.8)9.0 (3.1)8.9 (3.3)9.3 (3.0)
Weight, n (%)
  1532 kg24 (55.8)21 (53.8)23 (54.8)21 (53.8)89 (54.6)
  >3250 kg19 (44.2)18 (46.2)19 (45.2)18 (46.2)74 (45.4)
Gender, n (%)
  F, spayed25 (58.1)21 (53.8)26 (61.9)16 (41.0)*88 (54.0)
  F, intact0001 (2.6)1 (0.6)
  M, neutered15 (34.9)15 (38.5)16 (38.1)22 (56.4)68 (41.7)
  M, intact3 (7.0)3 (7.7)006 (3.7)
Breed, n (%)
  Large mixed breed12 (27.9)11 (28.2)13 (31.0)17 (43.6)53 (32.5)
  Labrador Retriever8 (18.6)6 (15.4)9 (21.4)7 (17.9)30 (18.4)
  Golden Retriever4 (9.3)3 (7.7)4 (9.5)3 (7.7)14 (8.6)
  German Shepherd4 (4.9)4 (10.3)1 (2.4)1 (2.6)10 (6.1)
CBPI pain interference5.2 (2.0)4.8 (2.0)5.1 (2.3)5.2 (2.1)5.1 (2.1)
CBPI pain severity4.2 (1.8)4.1 (1.9)4.2 (1.9)4.4 (1.9)4.2 (1.9)
CBPI overall impression, n (%)
  Excellent1 (2.3)2 (5.1)4 (9.5)3 (7.7)10 (6.1)
  Very good11 (25.6)10 (25.6)16 (38.1)7 (17.9)44 (27.0)
  Good22 (51.2)19 (48.7)14 (33.3)23 (59.0)78 (47.9)
  Fair9 (20.9)7 (17.9)7 (16.7)6 (15.4)29 (17.8)
  Poor01 (2.6)1 (2.4)02 (1.2)
LOAD mobility24.0 (5.7)23.7 (4.9)23.1 (6.0)25.6 (5.6)24.1 (5.6)

*P = 0.040 versus placebo.