Table 1 Subject characteristics for each group.

Values are shown as mean, with SD in parentheses.

CN A−T−All A+T+MCI A+T+AD dementia A+T+
Number10028518466
Age in years72.8 (5.36)73.53 (7.39)72.9 (7.11)73.6 (8.51)
Gender (F/M)45/55126/15977/10732/34
Years of education16.1 (2.80)15.91 (2.88)16.1 (2.81)15.2 (3.11)*
Clinical follow-up in years4.82 (2.40)3.69 (2.00)*4.05 (1.94)*2.18 (0.473)*
ADNI-MEM score1.11 (0.58)−0.15 (0.74)*−0.07 (0.57)*−0.89 (0.5)*
ADAS13 score9.1 (4.32)20.19 (8.53)*18.67 (6.32)*29.66 (6.83)*
1–42 (pg/ml)1527 (311)639.62 (172.89)*657 (167)*552 (166)*
p-tau181 (pg/ml)16.4 (2.95)37.76 (13.12)*38.0 (13.5)*39.9 (13.5)*
Total tau (pg/ml)186.6 (33.3)370.9 (115.2)*374.6 (120.1)*386.9 (113.5)*
CSF sTREM2 (pg/ml)3762 (1841)4540 (2422)*4452 (2518)*4608 (2201)*

*Significantly (P < 0.05) different from cognitively normal controls (CN A−T−) via post hoc Tukey test.