Table 1 Blood biochemistry results from pigs with atherosclerosis treated with PBS (placebo) or S-HDL.

Data are presented as median [interquartile range]. Bolded values indicate P < 0.05. ALP, alkaline phosphatase; SGPT, serum glutamic pyruvic transaminase; ALT, alanine aminotransferase; SGOT, serum glutamic-oxaloacetic transaminase; GGT, gamma-glutamyl transferase; AST, aspartate aminotransferase; CPK, creatine phosphokinase; BUN, blood urea nitrogen.

PlaceboS-HDLP
ALP (U/liter)127 [87–175]85 [70–132]0.15
SGPT (ALT)
(U/liter)
45 [39–67]51 [38–65]0.94
SGOT (AST)
(U/liter)
69 [43–222]67 [53–160]0.80
GGT (U/liter)40 [34–78]41 [39–56]0.67
CPK (U/liter)740 [406–1817]796 [431–1024]0.94
Total bilirubin
(mg/dl)
0.2 [0.1–0.2]0.2 [0.2–0.3]0.28
  Direct bilirubin
(mg/dl)
0.0 [0.0–0.1]0.0 [0.0–0.1]>0.99
  Indirect bilirubin
(mg/dl)
0.1 [0.1–0.2]0.2 [0.1–0.3]0.37
Total protein (g/dl)6.6 [5.9–6.7]6.8 [6.5–7.1]0.21
  Albumin (g/dl)3.5 [3.4–4.0]4.0 [3.7–4.5]0.29
  Globulin (g/dl)2.6 [2.5–3.1]2.8 [2.5–2.9]0.81
  Albumin/
globulin ratio
1.4 [1.2–1.6]1.4 [1.3–1.8]0.75
BUN (mg/dl)12 [10–14]10 [8.5–17]0.79
Creatinine (mg/dl)0.9 [0.8–1.2]1.0 [0.9–1.2]0.69
BUN/creatinine
ratio
13 [9.1–17]11 [9.0–15]0.94
Glucose (mg/dl)76 [71–80]67 [34–69]0.03
Cholesterol (mg/dl)573 [450–628]507 [426–747]0.80
Triglycerides
(mg/dl)
62 [26–72]72 [48–186]0.31
Sodium (mM)140 [140–141]139 [136–141]0.20
Potassium (mM)4.4 [4.3–5.1]4.6 [4.1–7.5]0.44
Na/K ratio32 [28–33]30 [21–35]0.44
Magnesium (mg/dl)2.0 [1.9–2.4]2.1 [1.9–2.8]0.81
Calcium (mg/dl)10 [9.4–11]10 [9.9–10.2]0.88
Phosphorus (mg/dl)7.4 [7.2–7.9]6.9 [6.4–8.6]0.53
Bicarbonate (mM)22 [19–24]19 [17–24]0.49
Chloride (mM)99 [98–101]102 [97–105]0.49