Wilcoxon ranked sum was used for analysis of continuous values, and Pearson’s χ2 was used for categorical values. P values for comparison of the two right columns, P. aeruginosa-positive Pf phage − patients versus P. aeruginosa-positive Pf phage-positive.
| P. aeruginosa-negative by qPCR | P. aeruginosa-positive by qPCR | P | ||
| Pf phage-negative | Pf phage-positive | |||
| Subjects, n | 18 | 37 | 21 | — |
| Sex, % male | 72.2% | 51.4% | 52.4% | 0.94 |
| Age, years (±SD) | 23.2 ± 13.5 | 25.9 ± 11.0 | 33.4 ± 10.9 | 0.006 |
| FEV1, % predicted (±SD) | 50.3 ± 24.0 | 54.1 ± 20.1 | 58.7 ± 26.5 | 0.57 |
| BMI, Z score (±SD) | −0.16 ± 1.0 | 0.8 ± 0.85 | 0.09 ± 0.9 | 0.37 |
| CFTR genotype | ||||
| Homozygous F508del, n (%) | 5 (27.8%) | 17 (46.0%) | 11 (54.5%) | 0.52 |
| Heterozygous F508del, n (%) | 8 (44.4%) | 14 (37.8%) | 5 (23.8%) | |
| P. aeruginosa, copies/ml (range) | 0 | 2.2 × 108 (2.8 × 102–5.1 × 109) | 3.2 × 108 (1.5 × 105–1.9 × 109) | 0.01 |
| Pf phage, copies/ml (range) | 0 | 0 | 4.4 × 109 (1.3 × 106–3.1 × 1010) | — |