Table 1 Patient characteristics and microbiologic data in the Stanford CF cohort.

Wilcoxon ranked sum was used for analysis of continuous values, and Pearson’s χ2 was used for categorical values. P values for comparison of the two right columns, P. aeruginosa-positive Pf phage − patients versus P. aeruginosa-positive Pf phage-positive.

P. aeruginosa-negative
by qPCR
P. aeruginosa-positive by qPCRP
Pf phage-negativePf phage-positive
Subjects, n183721
Sex, % male72.2%51.4%52.4%0.94
Age, years (±SD)23.2 ± 13.525.9 ± 11.033.4 ± 10.90.006
FEV1, % predicted (±SD)50.3 ± 24.054.1 ± 20.158.7 ± 26.50.57
BMI, Z score (±SD)−0.16 ± 1.00.8 ± 0.850.09 ± 0.90.37
CFTR genotype
  Homozygous F508del, n (%)5 (27.8%)17 (46.0%)11 (54.5%)0.52
  Heterozygous F508del, n (%)8 (44.4%)14 (37.8%)5 (23.8%)
P. aeruginosa, copies/ml
(range)
02.2 × 108
(2.8 × 102–5.1 × 109)
3.2 × 108
(1.5 × 105–1.9 × 109)
0.01
Pf phage, copies/ml (range)004.4 × 109
(1.3 × 106–3.1 × 1010)