Table 1 Clinical and demographic characteristics.

ADI, autism diagnostic interview; ADOS, autism diagnostic observation schedule; PDD-NOS, pervasive developmental disorder not otherwise specified; RRB, restricted and repetitive behaviors; SRS, social responsiveness scale.

EU-AIMS LEAPABIDE IABIDE IIInFoR
ASDTDStats
(test value,
df, and
P value)
ASDTDStats
(test value,
df, and
P value)
ASDTDStats
(test value,
df, and
P value)
ASDTDStats (test value, df, and P value)
n2021922993763063913425
Male/female142/
60
124/
68
1.5, 1,
0.226
268/31313/635.7, 1,
0.017
262/
44
263/
127
30.4, 1,
<0.001
26/819/60.0, 1,
0.967
Age ± SD17.5 ±
5.3
17.4 ±
5.7
0.1, 392,
0.915
17.5 ±
7.7
17.7 ±
7.8
−0.3, 673,
0.776
14.0 ±
6.8
13.6 ± 6.20.8, 695,
0.428
29.5 ±
8.9
30.6 ±
8.3
0.5, 57,
0.638
Child/
adolescent/
adult
35/76/
91
43/71/
78
1.7, 2,
0.434
69/118/
112
85/147/
144
0.1, 2,
0.974
147/85/
74
234/77/
80
10.3, 2,
0.006
0/0/
34
0/0/
25
IQ (mean ±
SD, n)
106 ±
14.9
109 ±
12.6
−2.1, 392,
0.033
106.3 ±
16.0
112.0 ±
12.1
−5.3, 673,
<0.001
107.0 ±
16.0
115.7 ±
12.5
−8.0, 695,
<0.001
104.3 ±
18.7
108.6 ±
17.5
0.9, 54,
0.392
DSM IV
diagnosis
(none/ASD/
Asperger/
PDD-NOS)
16/204/
60/16
121/55/
78/52
On medication (n)5426118117
ADOS total
(mean ± SD, n)
10.1 ±
4.9, 170
11.9 ±
3.7, 259
1.3 ±
1.4, 30
15.4, 287,
<0.001
10 ±
3.7, 167
1.8 ±
1.7, 38
13.4, 203,
<0.001
ADI social
(mean ± SD, n)
15.7 ±
6.7, 191
19.9 ±
5.4, 184
18.7 ±
5.8, 217
16.2 ±
6.4, 25
ADI
communication
(mean ± SD, n)
12.9 ±
5.8, 191
15.8 ±
4.7, 185
14.9 ±
4.6, 217
9.4 ±
5.3, 25
ADI RRB
(mean ± SD, n)
4.1 ±
2.6, 191
6.1 ±
2.5, 185
5.5 ±
2.5, 217
2.2 ±
1.3, 22
SRS t-score68.9 ±
11.9,
165
45.9 ±
7.5, 90
16.6, 253,
<0.001
75.4 ±
13.5, 256
VABS adaptive
behavior
composite
(mean ± SD, n)
70.0 ±
12.3, 87
77.3 ±
13.7, 60
82.8 ±
10.9, 61
VABS daily
living skills
(mean ± SD, n)
71.0 ±
13.5, 87
83.2 ±
15.2, 60
87.4 ±
10.4, 61
VABS
socialization
(mean ± SD, n)
69.3 ±
16.6, 88
75.0 ±
16.5, 60
82.5 ±
12.5, 61
VABS
communication
(mean ± SD, n)
77.3 ±
14.9, 88
79.3 ±
15.5, 60
87.3 ±
13.9, 61