Table 1 GDP-l-fucose synthase transcripts and peptides identified in brain tissue.

RPKM, reads per kilobase of exon model per million mapped reads; PSMs, peptide spectrum matches. Proteome data correspond to white matter (WM) and gray matter (GM) from patients with MS (MS; n = 15) and controls without MS (non-MS; n = 9). In bold are GDP-l-fucose synthase values.

ProteinGene
ID
TranscriptomeUniProt
ID
Peptide sequenceResiduesProteome (PSMs)DistinctProtein
RPKMMSNon-MSTotalPeptidesCoverage
LI*LIILIIIWMGMWMGM#%
GDP-l-fucose synthaseTSTA32.172.022.67Q13630ILVTGGSGLVGK10–2112121212481756.0
VVADGAGLPGEDWVFVSSK26–441212121248
DADLTDTAQTR45–551212121248
VQPTHVIHLAAMVGGLFR61–7899927
YNLDFWR82–881212121248
YNLDFWRK82–8911
NVHMNDNVLHSAFEVGAR90–10713131339
NVHMNDNVLHSAFEVGARK90–10833
VVSCLSTCIFPDK109–12133
MIDVQNR149–155224
RMIDVQNR148–155224
SSGSALTVWGTGNPR200–21433
SSGSALTVWGTGNPRR200–21511
TTYPIDETMIHNGPPHNSNFGYSYAK222–24733
EYNEVEPIILSVGEEDEVSIK233–25333
TYLPDFR291–2971212121248
LRTYLPDFR289–29722
63878895333
Myelin basic proteinMBP37.2028.9759.21P0268699387198586537148079.6
Myelin proteolipid proteinPLP1458.31341.43431.91P602011481531291575871330.6
Myelin-oligodendrocyte
glycoprotein
MOGQ166532161992222168532849.8
Myelin-associated
glycoprotein
MAG16.2910.8326.84P209162432322212439393436.9
Myelin-associated
oligodendrocyte
basic protein
MOBP14.4811.1619.82Q138752012271473626.2
Oligodendrocyte myelin
glycoprotein
OMG5.215.073.26P235151441551361555901328.8
2′,3′-cyclic-nucleotide
3′-phosphodiesterase
CNPP09543116898511571060437011296.4

*LI and LIII, active lesions in which TCC21.1 was clonally expanded. LII, inactive lesion in which TCC21.1 was not identified.