Table 2 Comparison of NGS cancer sequencing panels.

TP, true positive; FN, false negative; FP, false positive; 95% CI, 95% confidence interval; Indel, insertion or deletion; PPV, positive predictive value.

Performance
metric
CancerSelect 125Oncomine comprehensive assayTruSeq AmpliconCancer Panel
TPFNPoint
estimate
(%)
95% CITPFNPoint
estimate
(%)
95% CITPFNPoint
estimate
(%)
95% CI
SBS sensitivity30010085.9–10029196.780.9–99.8151550.033.2–66.8
Indel
sensitivity
6010051.7–1005183.336.4–99.13350.018.8–81.2
TPFPPoint
estimate
(%)
95% CITPFPPoint
estimate
(%)
95% CITPFPPoint
estimate
(%)
95% CI
SBS PPV30010085.9–100291763.047.5–76.4151698.24.8–13.3
Indel PPV6010051.7–1005010046.3–1003633.39.0–69.1