Table 2 Cox regression analysis in TCGA LGG patients.

BCL3 expression is also significant with inclusion of grade into analysis (P = 0.042).

CovariateUnivariate regression
HR95% CIP
BCL3 expression1.4311.186–1.7350.000
MGMT methylation0.2680.167–0.4310.000
IDH1 mutation0.1030.062–0.1730.000
1p/19q co-deletion0.4860.281–0.8370.009
Grade (II or III)3.5542.194–5.7580.000
Radiotherapy0.4040.202–0.8070.010
Chemotherapy0.2190.068–0.7060.011
Procurement method1.4020.911–2.1590.125
Age1.0601.042–1.0790.000
CovariateMultivariate regression
HR95% CIP
BCL3 expression1.3741.096–1.7220.006
MGMT methylation0.6850.363–1.2930.243
IDH1 mutation0.4010.186–0.8640.020
1p/19q co-deletion0.6460.339–1.2290.183
Age1.0641.042–1.0860.000