Table 1 Human subject cohort and clinical characteristics.

SCLE02, SCLE03, SCLE05, and SCLE06 were de-identified serum or biopsy samples, so additional clinical information was unavailable. Ro60 column indicates the presence or absence of anti-Ro60 serum IgG. F, female; M, male; HCQ, hydroxychloroquine; NA, not available. Additional clinical information is available in tables S2 and S3.

SubjectDiagnosisSexAge (years)HLA-DR3HLA-DR15Ro60Immunosuppressive
medications
HCQ
SLE01SLEF40+Azathioprine
SLE02SLEF47++Rituximab
Prednisone 5 mg daily
SLE03SLEF49Mycophenolate mofetil
Prednisone 7.5 mg daily
+
SLE04SLEF29+Discontinued
mycophenolate mofetil
and prednisone against
medical advice 1 month
prior
SLE05SLEF49++Prednisone 1 mg daily+
SLE06SLEF40+Mycophenolate mofetil
Prednisone 5 mg daily
+
SLE07SLEF31+
SLE08SLEF52++
SLE09SLEF34++
SLE10SLEF47++++
SLE11SLEF31++Mycophenolic acid
Prednisone 10 mg daily
+
SLE12DLEF54++
SLE13SLEF26++Mycophenolic acid
Methotrexate
Prednisone 7.5 mg daily
+
SLE14SLEF32
SLE15SLEF44+
SLE18SLEF33+NANA
SCLE01SCLEF75++Azathioprine+
SCLE04SCLEM72+