Table 2. Functional characterization and histological analysis of kidneys 6 to 8.

The mean RBF, urine output, level of oxygen consumption, and perfusate pH levels at baseline (after 30 min of perfusion but before the administration of NPs), 2 hours, 4 hours, 6 hours, and 8 hours of perfusion. ATN, acute tubular necrosis.

Case 6Case 7Case 8
RBF (ml/min per 100 g)
  Baseline524125
  2 hours608278
  4 hours769098
  6 hours96102119
  8 hours120107135
Urine output (ml)
  Baseline5598
  2 hours1115455
  4 hours135126101
  6 hours15412781
  8 hours14313512
  Total598451257
Oxygen consumption
(ml/min per g)
  Baseline38.546.057.9
  2 hours43.961.056.6
  4 hours52.267.470.9
  6 hours70.275.852.1
  8 hours84.781.099.4
pH
  Baseline7.217.237.34
  2 hours7.277.417.35
  4 hours7.347. 427.35
  6 hours7.377.387.28
  8 hours7.377.407.28
Histology
  BaselineNo ATNNo ATNNo ATN
  2 hoursNo ATNNo ATNNo ATN
  4 hoursNo ATNNo ATNNo ATN
  6 hoursNo ATNFocal mild
ATN
No ATN
  8 hoursFocal mild
ATN
No ATNFocal mild
ATN