Table 1. Characteristics of sCJD and vCJD patients.

sCJD, sporadic Creutzfeldt-Jakob disease; vCJD, variant CJD; MRI, magnetic resonance imaging; CSF, cerebrospinal fluid.

Mean age, years (SD)59.4 (15.3)
Mean duration, months (SD)10.7 (10.8)
Male/female10:13
(43.5%:56.5%)
Race, n (%)
  White19 (82.6%)
  Black0 (0)
  Hispanic1 (4.3%)
  Mixed1 (4.3%)
  Unknown2 (8.7%)
Cognitive symptoms, n (% with known symptoms)20 (100%)
Myoclonus, n (% with known symptoms)10 (52.6%)
Cerebellar symptoms, n (% with known symptoms)18 (94.7%)
Visual symptoms, n (% with known symptoms)11 (57.9%)
Pyramidal symptoms, n (% with known symptoms)8 (42.1%)
Extrapyramidal symptoms, n (% with known
symptoms)
8 (42.1%)
PSWCs on EEG, n (%)*0 (0)
Brain MRI suggestive of prion disease, n (%)16 (88.9%)
CSF 14-3-3 positive, n (%)13 (59.1%)
Mean CSF τ concentration, pg/ml (SD)7136.8 (6237.0)
Prion disease subtype, n (%)
  MM16 (26.1%)
  MM23 (13%)
  MV11 (4.3%)
  VV11 (4.3%)
  VV24 (17.4)
  MV1-23 (13%)
  VV1-21 (4.3)
  MM1-22 (8.7)
  vCJD2 (8.7)

*Of 23 CJD patients, electroencephalography (EEG) was available for 13 cases. Four patients exhibited normal EEGs, and nine had abnormal EEGs but did not have periodic sharp wave complexes (PSWCs).

†Study of Zerr et al. (16).

‡Study of Belay et al. (17).