Table 3. End point RT-QuIC quantitation of seeding activity in brain and skin samples from CJD patients.
Log SD50 per milligram of tissue*
Patient no.DiagnosisBrainS1 skinP4 skin
1sCJDVV1>9.76.94.8
2sCJDMM1>8.5>6.84.9
3sCJDVV1-28.05.1≤3.0
4sCJDMM29.26.84.7
5sCJDMV2>8.76.54.1
6vCJDMM2>8.25.03.6
7vCJDMM27.7≤3.0≤3.5

*Log seeding dose 50 (SD50) was calculated, as described in Materials and Methods.