Table 1. Clinical and biochemical characteristics of subjects.

Data are presented as the means ± SD. Mann-Whitney test was used. F, female; M, male; GGT, γ-glutamyltranspeptidase; ALT, alanine aminotransferase; AST, aspartate aminotransferase; TB, total bilirubin.

VariableDiscovery cohortValidation cohort #1Validation cohort #2
BAIHCP*BAIHCP*BAP
Number of patients35353534105
Age (days)62 ± 2857 ± 310.4367 ± 3066 ± 350.2472 ± 280.07
Gender (F/M)16/196/2917/1812/2253/52
AST (U/liter)268 ± 381246 ± 2080.61211 ± 135270 ± 2580.59233 ± 1920.65
ALT (U/liter)176 ± 177187 ± 1650.80135 ± 90207 ± 2210.60167 ± 1250.77
TB (mg/dl)8.4 ± 3.28.5 ± 4.40.858.8 ± 3.98.9 ± 4.60.978.3 ± 3.00.99
GGT (U/liter)619 ± 361179 ± 169<0.0001744 ± 519241 ± 305<0.0001842 ± 6290.11

*Comparison between BA and IHC.

†Comparison between BA in the discovery cohort and validation cohort #2