Table 3. THBS2 concentration cutoff points based on percentiles of distribution in control plasma samples.
MarkerPhase 2aPhase 2b
CutoffSensitivitySpecificitySensitivitySpecificity
CA19-9 (≥55)69.1410077.6698.57
THBS2 (ng/ml)
  95%3633.3396.2558.3893.57
  96%3733.3397.5057.3695.00
  97%3830.8697.5053.8196.43
  98%4028.4097.5053.3097.86
  99%4224.6997.5051.7899.29
  100%73.47.4110023.35100
CA19-9 (≥55) and THBS2 (ng/ml)
  95%3674.0796.2588.3292.86
  96%3774.0797.5088.3294.29
  97%3874.0797.5087.8295.71
  98%4074.0797.5087.8297.14
  99%4272.8497.5087.3197.86
  100%73.469.1410081.7398.57