Table 2. Associations of brain or CSF poly(GP) with c9ALS-like pathological features in (G4C2)66 mice.

Spearman’s r correlation coefficients, 95% CIs, and P values are presented.

CharacteristicBrain poly(GP)CSF poly(GP)
Spearman’s r (95% CI)PSpearman’s r (95% CI)P
Brain poly(GP) (n = 20)0.74 (0.42–0.89)0.0002
Brain poly(GA) (n = 20)0.92 (0.80–0.97)<0.00010.75 (0.44–0.90)0.0002
G4C2 repeat–containing mRNA (n = 20)0.87 (0.69–0.95)<0.00010.64 (0.26–0.85)0.0025
Cells with foci in motor cortex (%) (n = 12)0.78 (0.35–0.94)0.0040.82 (0.45–0.95)0.0017