Table 1. Summary of clinical characteristics of evaluable patients treated with cytokine-induced memory-like NK cells.

All patients were Caucasian. KIR-ligand mismatch is reported in the NK cell donor versus patient vector. Patient 012 was reenrolled at a higher dose level as patient 019. UPN, universal patient number; WHO, World Health Organization; DLT, dose-limiting toxicity; M, male; F, female; IWG, International Working Group; TF-PD, treatment failure due to progressive disease; CR, complete remission; MLFS, morphologic leukemia-free state; CRi, CR with incomplete blood count recovery; MDS, myelodysplastic syndrome.

UPNDose levelGenderAge
(years)
WHO
diagnosis
Number of previous
therapies
Pretreatment
BM blast (%)
KIR-ligand
mismatch
IWG
response
DLTGVHD
0011M73M2216YesTF-PDNoNo
0061M70M0328YesTF-PDNoNo
0071M77M0147YesCRNoNo
0082M76t-AML317YesTF-PDNoNo
0092F73M1380NoMLFSNoNo
0122F71M5315YesCRNoNo
0173M64t-AML369YesTF-PDNoNo
0193F71M5415YesCRNoNo
0203M60MDS-AML113YesCRiNoNo