Table 2. Clinical comparison of patients by JAK2 status.

Characteristics of patients with complete tNGS data. OS, overall survival; RFS, recurrence-free survival.

JAK2-amplifiedJAK2-normal
No.7 (10.9%)57 (89.9%)
Median age39.947.6
Premenopausal5 (71.4%)33 (57.9%)
Miller-Payne
I4 (57.1%)9 (15.8%)*
II1 (14.2%)15 (26.3%)
III0 (0%)5 (8.8%)
IV0 (0%)6 (10.5%)
V0 (0%)5 (8.8%)
Unknown2 (28.7%)17 (29.8%)
OS (median)10.824.4
RFS (median)7.921.8

*P = 0.027, two-tailed Fisher’s exact test.

P = 0.002, two-sided log-rank test.

P = 0.015, two-sided log-rank test.