Table 2. Serologic response of flavivirus-naïve subjects after vaccination with TV003.
Peak geometric mean titer, reciprocal (median)*
nDEN1DEN2DEN3DEN4
2447 (29)84 (78)152 (167)270 (276)
Range<5–4991–71031–53343–5025
% with PRNT50 ≥1:10
nDEN1DEN2DEN3DEN4
2491.7100100100
Multivalent responses (cumulative)
nTetraTriBiMono
2491.7%8.3% (100)00

*Titer calculated only for those subjects who had a PRNT50 ≥10. The peak titer is calculated from titers obtained through study 90 after vaccination (days 28, 56, and 90).