Table 3. External validation of the ARI classifier (combined bacterial ARI, viral ARI, and noninfectious classifiers).

Five Gene Expression Omnibus data sets were identified on the basis of the inclusion of at least two of the relevant clinical groups: viral ARI, bacterial ARI, and noninfectious illness (SIRS).

Clinical assignment
BacterialViralSIRSAUC
GSE6269: Hospitalized children with
influenza A or bacterial infection
Classifier-predicted assignmentBacterial8410.95
Viral226
GSE42026: Hospitalized children with
influenza H1N1/09, RSV (respiratory
syncytial virus), or bacterial infection
Bacterial1530.90
Viral635
GSE40396: Children with adenovirus,
HHV-6 (human herpesvirus 6),
enterovirus, or bacterial infection
Bacterial710.93
Viral332
GSE20346: Hospitalized adults with
bacterial pneumonia or influenza A
Bacterial2600.99
Viral118
GSE42834: Adults with bacterial
pneumonia, lung cancer, or sarcoidosis
Bacterial1830.99
SIRS181