Five Gene Expression Omnibus data sets were identified on the basis of the inclusion of at least two of the relevant clinical groups: viral ARI, bacterial ARI, and noninfectious illness (SIRS).
Clinical assignment | ||||||
Bacterial | Viral | SIRS | AUC | |||
GSE6269: Hospitalized children with influenza A or bacterial infection | Classifier-predicted assignment | Bacterial | 84 | 1 | 0.95 | |
Viral | 2 | 26 | ||||
GSE42026: Hospitalized children with influenza H1N1/09, RSV (respiratory syncytial virus), or bacterial infection | Bacterial | 15 | 3 | 0.90 | ||
Viral | 6 | 35 | ||||
GSE40396: Children with adenovirus, HHV-6 (human herpesvirus 6), enterovirus, or bacterial infection | Bacterial | 7 | 1 | 0.93 | ||
Viral | 3 | 32 | ||||
GSE20346: Hospitalized adults with bacterial pneumonia or influenza A | Bacterial | 26 | 0 | 0.99 | ||
Viral | 1 | 18 | ||||
GSE42834: Adults with bacterial pneumonia, lung cancer, or sarcoidosis | Bacterial | 18 | 3 | 0.99 | ||
SIRS | 1 | 81 |