Table 1 Building and broadening collaborations.

LACRN timeline for collaborative cancer research efforts.

2009 • LACRN formed by LOIs*
• First planning meeting, Bethesda, MD, USA
• MPBC study protocol and SOP developed at workshop, Santiago, Chile
2010 • Initiation of monthly committee calls via teleconference and webinars
• Pathology workshop, Rio de Janeiro, Brazil
• Biobanking and molecular biology workshops, Montevideo, Uruguay
• Bioinformatics workshop, Bethesda, MD, USA
• Second LACRN annual meeting, Rio de Janeiro, Brazil
2011 • Biobanks established across LACRN countries
• Residual cancer burden training, MD Anderson Cancer Center, Houston, TX, USA
• Release of manual of operations and database in three languages
• Start of patient recruitment for MPBC
• Study monitoring plan implemented
• Third LACRN annual meeting, Guadalajara, Mexico
2012 • First interim data analysis
• First meeting of vDCAT, Buenos Aires, Argentina
• Second interim data analysis
• Fourth LACRN annual meeting, Buenos Aires, Argentina
2013–2014 • Bioinformatics training, Rio de Janeiro, Brazil
• Third interim data analysis
• REBLAC/RINC** and LACRN pathology and biobanking workshop, Rio de Janeiro, Brazil
• MPBC study closed to patient accrual, December 2013
• LACRN strategic planning meeting, Bethesda, MD, USA
• Future studies meeting, Lima, Peru

*LOIs, letters of intent to collaborate; **REBLAC/RINC, Red de Biobancos de Latinoamérica y Caribe/Red de Institutos Nacionales de Cáncer.