Table 2. Required SREs in the test group of samples (group III).

The 648 RNA elements describing fertile sperm were tested in nine samples. (i) All samples that were obtained from an independent fertility clinic and achieved LB presented with all required SREs. LB was achieved spontaneously or by IUI for samples 4 and 5, whereas the remaining three cases (1 to 3) directly used ART. (ii) Samples with known female factor. A single instance (sample 6) shows the absence of two SREs as well as a known female factor. It is possible that with a GC (gestational carrier), the pregnancy was rescued by ART despite the absence of these two SREs.

TreatmentFinal
outcome
Required
SREs absent
(i) Samples from independent fertility clinic
1IVF (LB)LB0
2IVF (NLB)/ICSI (LB)LB0
3IVF (NLB)/ICSI (LB)LB0
4IUI (LB)LB0
5Natural conceptionLB0
(ii) Samples with known female factor
6ICSI (LB with GC)LB2
7ICSI (NLB)/ICSI (LB with GC)LB0
8ICSI (NLB)/ICSI (LB with GC)LB0
9TIC (NLB)/IUI (NLB)NLB0