Table 3. Linear regression analysis of change in DAS at day 30 on laboratory features.

Features with P ≤ 0.05 (t test) are shown in the table. The intercepts are not shown. % Foxp3+ Treg is the % of the CD4+CD25hiCD127lo Treg cells expressing Foxp3. Emax = peak value/baseline value × 100%; Emin = trough value/baseline value × 100%. FDR, false discovery rate (calculated using Benjamini-Hochberg correction).

FeaturesEstimatePFDRR2
% Teff, day 60.780.0040.0560.41
% Foxp3+ Treg, day 6−0.650.0090.140.36
% CD16hiCD14+ monocytes, day 30−0.660.020.420.35
Emin Teff0.730.0050.0640.37
Emax Treg/Teff−0.710.0010.0090.57
Anti-CCP IgA/IgG titer, day 67.420.020.0460.42
Anti-CCP IgA/IgG titer, day 301.730.0050.0460.39