Table 2. Antipneumococcal activity of select amSPCs against drug-sensitive and drug-resistant isolates.

MIC testing for amSPC activity against a panel of S. pneumoniae isolates.

TreatmentMIC (μg/ml)
Drug-sensitiveDrug-resistant
R6T4XD39XBHN97xA66.1xOVA2BAA-1407Daw7Daw8Daw9Daw62Daw64Daw19Daw26Daw27Daw478249ATCC700904
SPC1313136613132525132525255025252525
1332223633333666636
2663336136666613131313613
33166322236633213
Penicillin G≤0.2≤0.2≤0.2≤0.2≤0.2≤0.22332323333>2>2
Cefotaxime130.4330.2
Erythromycin≤0.2150≤0.2≤0.22≤0.2≤0.210.110.03>22
Streptomycin13613131313502525>2002525>200>200