Table 2. Serum ALT activity and albumin and cholesterol concentrations in NPC cats.

Mean ± SD for serum ALT, albumin, and total cholesterol of 24-week-old cats. P values are provided for groups significantly different from untreated normal control cats (*) or significantly different from untreated NPC cats (†). SD is not provided for 4000 mg/kg group, where n = 2.

Untreated
normal control
Untreated
NPC
1000 mg/kg
SC
4000 mg/kg
SC
8000 mg/kg
SC
30 mg
IC
120 mg
IC
120 mg IC and
1000 mg/kg SC
ALT (U/liter)62.1 ± 15.4395.8 ± 169
*P = 0.0000002
128.1 ± 127.6
P = 0.0003
37.577 ± 66.9
P = 0.00001
295.3 ± 107
*P = 0.003
223.8 ± 87
*P = 0.003
P = 0.003
135 ± 91
P = 0.00004
Albumin (g/dl)2.9 ± 0.32.6 ± 0.3
*P = 0.00035
2.8 ± 0.23.03.3 ± 0.38
*P = 0.002
P = 0.000002
2.5 ± 0.01
*P = 0.00002
2.5 ± 0.2
*P = 0.00006
3.0 ± 0.3
P = 0.008
Cholesterol
(mg/dl)
120.3 ± 23240.3 ± 72
*P = 0.000001
189.9 ± 48.5
*P = 0.004
P = 0.04
131166 ± 58
P = 0.04
191.2 ± 37.3
*P = 0.004
P = 0.04
180.6 ± 22.4
*P = 0.0001
P = 0.004
166 ± 34.6*
*P = 0.007
*P = 0.002