Table 1.

Global burden of selected diseases for which new and improved vaccines are needed.

DiseaseAnnual global cases (in millions)Annual global deaths (in millions)
Malaria 207.00.627
Dengue96.00.02
Tuberculosis8.61.300
Influenza4.00.375
HIV2.31.600
Total estimated burden317.93.9

Malaria cases and deaths are estimates from the 2013 World Malaria Report (21). Dengue global cases are estimates from 2010 (22). Tuberculosis cases and deaths are estimates from 2013, WHO Global TB report (25). Influenza cases and deaths estimates are from WHO Fact Sheet 2014 (26).