Table 1. Subject demographics and cellular characteristics of the CNS tissue.
SubjectDisease stateAgeGenderHistopathologic findings
M1Relapsing-remitting MS (RRMS)39MNormal-appearing white matter.
M2Secondary progressive MS53FSmall chronic periventricular white matter lesion without both perivascular infiltrations
and microglial activation.
M3Primary progressive MS74FSmall chronic white matter lesion with perivascular infiltrates and microglial activation.
M4Chronic progressive MS80MSmall chronic periventricular white matter lesion without both perivascular
infiltrations and microglial activation.
M5Chronic MS63FLarge chronic white matter lesion with occasional minimal perivascular infiltrates. No
microglial activation.