Mutations unique to colistin-resistant isolates.
Strain | Unique mutations |
Patient 2 (resistant) | Coding indel in query: GA at position 321 of 1221 in KPNIH1_08595 (microcin B17 transporter) |
Noncoding SNP: G→A, between KPNIH1_06013 (hypothetical protein) and KPNIH1_06008 (putative acid phosphatase) | |
Patient 8 (initial) | Coding SNP: CTG→ATG (L→M) at 130 of 309 in KPNIH1_18808 (putative membrane protein) |
Coding SNP: ACC→ATC (T→I) at 1106 of 1119 in KPNIH1_07189 (L-Ala-D/L-Glu epimerase) (methyl viologen resistance protein SmvA) | |
Noncoding SNP: G→T, between KPNIH1_24168 (putative phosphatase) and KPNIH1_24173 (hypothetical protein) | |
Coding SNP: GGC→TGC (G→C) at 811 of 1110 in KPNIH1_05438 (putative transport protein) | |
Coding SNP: CTT→CCT (L→P) at 941 of 1476 in KPNIH1_07179 | |
Noncoding SNP: G→T, between KPNIH1_15985 (aspartate kinase III) and KPNIH1_15980 (glucose-6-phosphate isomerase) |