Table 1

Genetic background and HLA haplotypes of humanized BLT mice. Each group of mice reconstituted with a single human donor’s tissues and cells is designated by a group number, for example, M20; individual mice are further designated with a dash followed by the mouse number, for example, M20-07. Bold indicates groups from which sequence was examined. Underlined group numbers designate groups from which viral load data were determined. NS, NOD/SCID; NSG, NOD/SCID/IL2Rγc−/−; ND, not determined.

GroupGenetic
background
Number
of mice
HLA-A*HLA-B*HLA-C*
M16NS101:0136:0135:0249:0104:0107:01
M20NS601:0102:0108:0152:0103:0307:01
M24NS802:0126:0115:0127:0501:0203:04
M30NS701:0101:0108:0108:0107:0107:01
M31NSG624:0274:0014:0257:0302:0206:02
M33NSG102:0124:03NDND03:0307:02
M47NSG702:0624:0215:0240:0103:0404:03
M51NSG603:0111:0135:0157:0104:0106:02