Table 3

Electrophysiological intervals recorded in wild-type and Mecp2Null/+ mice. Data are expressed as means ± SEM.

WT (4 months)
(n = 5)
Mecp2Null/+ (4 months)
(n = 13)
WT (10 months)
(n = 6)
Mecp2Null/+ (10 months)
(n = 7)
RR (ms)122.4 ± 4.7121.7 ± 5.2117.7 ± 2.1116.9 ± 3.1
PQ (ms)31.6 ± 2.733.5 ± 3.230.0 ± 0.831.3 ± 0.8
QRS (ms)8.2 ± 0.58.9 ± 0.97.5 ± 0.38.6 ± 0.3*
QT (ms)35.6 ± 1.535.8 ± 2.233.7 ± 1.042.3 ± 1.4
QTc (ms)50.7 ± 1.651.2 ± 1.950.3 ± 0.658.1 ± 1.5
SCL (ms)122.6 ± 4.7122.5 ± 5.2117.7 ± 2.2116.9 ± 3.1
AV (ms)38.8 ± 3.039.8 ± 3.237.3 ± 1.639.1 ± 1.7

*P < 0.05 versus age-matched wild type.

P < 0.001 versus age-matched wild type.