Barriers to enrollment in clinical trials.
• Insufficient physician time/interest |
• Lack of dedicated research staff |
• Lack of equipoise in clinical trial design |
• Increasing protocol eligibility requirements and protocol complexity |
• Lack of reimbursement for physician management of patients in trials |
• Off-label prescribing of drugs |
• Lack of insurance coverage for patients participating in clinical trials |
• Regulatory liability and burden |
• Insufficient patient awareness/demand |