RT Journal Article SR Electronic T1 Targeting the glucocorticoid receptor in breast and prostate cancers JF Science Translational Medicine FD American Association for the Advancement of Science SP 305ps19 OP 305ps19 DO 10.1126/scitranslmed.aac7531 VO 7 IS 305 A1 Kach, Jacob A1 Conzen, Suzanne D. A1 Szmulewitz, Russell Z. YR 2015 UL http://stm.sciencemag.org/content/7/305/305ps19.abstract AB Steroid receptors for androgens and estrogens have essential roles in prostate and breast cancers. Recently, glucocorticoid receptor (GR) activity has also been proposed as having an important role in these cancers. Underscoring the cooperative nature of nuclear receptor activity, data now suggest that GR function in prostate and breast cancers is dependent on the tumor’s concomitant androgen or estrogen receptor activity.