PT  - JOURNAL ARTICLE
AU  - Cunnington, Aubrey J.
AU  - Walther, Michael
AU  - Riley, Eleanor M.
TI  - Piecing Together the Puzzle of Severe Malaria
AID  - 10.1126/scitranslmed.3007432
DP  - 2013 Nov 13
TA  - Science Translational Medicine
PG  - 211ps18--211ps18
VI  - 5
IP  - 211
4099  - http://stm.sciencemag.org/content/5/211/211ps18.short
4100  - http://stm.sciencemag.org/content/5/211/211ps18.full
AB  - Severe malaria manifests as several overlapping syndromes with high mortality. Interaction of parasites with endothelial protein C receptors and high parasite biomass have recently been identified as key determinants of severe disease. However, gaps in our understanding of severe malaria might hinder translation of these findings into new therapies.