PT  - JOURNAL ARTICLE
AU  - Bilican, Bilada
AU  - Serio, Andrea
AU  - Barmada, Sami J.
AU  - Nishimura, Agnes Lumi
AU  - Sullivan, Gareth J.
AU  - Carrasco, Monica
AU  - Phatnani, Hemali P.
AU  - Puddifoot, Clare A.
AU  - Story, David
AU  - Fletcher, Judy
AU  - Park, In-Hyun
AU  - Friedman, Brad A.
AU  - Daley, George Q.
AU  - Wyllie, David J. A.
AU  - Hardingham, Giles E.
AU  - Wilmut, Ian
AU  - Finkbeiner, Steven
AU  - Maniatis, Tom
AU  - Shaw, Christopher E.
AU  - Chandran, Siddharthan
TI  - Comment on “Drug Screening for ALS Using Patient-Specific Induced Pluripotent Stem Cells”
AID  - 10.1126/scitranslmed.3005065
DP  - 2013 Jun 05
TA  - Science Translational Medicine
PG  - 188le2--188le2
VI  - 5
IP  - 188
4099  - http://stm.sciencemag.org/content/5/188/188le2.short
4100  - http://stm.sciencemag.org/content/5/188/188le2.full
AB  - Egawa et al. recently showed the value of patient-specific induced pluripotent stem cells (iPSCs) for modeling amyotrophic lateral sclerosis in vitro. Their study and our work highlight the need for complementary assays to detect small, but potentially important, phenotypic differences between control iPSC lines and those carrying disease mutations.