RT Journal Article SR Electronic T1 From Optogenetic Technologies to Neuromodulation Therapies JF Science Translational Medicine FD American Association for the Advancement of Science SP 177ps6 OP 177ps6 DO 10.1126/scitranslmed.3003100 VO 5 IS 177 A1 Williams, Justin C. A1 Denison, Timothy YR 2013 UL http://stm.sciencemag.org/content/5/177/177ps6.abstract AB The field of optogenetics has provided new insight into neuronal communication and complex brain function. Now, scientists eagerly anticipate clinical application of this technology, with the hope that it will help improve treatments for various neurological disorders. However, the translational hurdles are high. In this Perspective, we highlight the technical, practical, and regulatory hurdles that lie ahead along the path towards making optogenetic neuromodulation therapies a reality in the clinic.