PT  - JOURNAL ARTICLE
AU  - Williams, Justin C.
AU  - Denison, Timothy
TI  - From Optogenetic Technologies to Neuromodulation Therapies
AID  - 10.1126/scitranslmed.3003100
DP  - 2013 Mar 20
TA  - Science Translational Medicine
PG  - 177ps6--177ps6
VI  - 5
IP  - 177
4099  - http://stm.sciencemag.org/content/5/177/177ps6.short
4100  - http://stm.sciencemag.org/content/5/177/177ps6.full
AB  - The field of optogenetics has provided new insight into neuronal communication and complex brain function. Now, scientists eagerly anticipate clinical application of this technology, with the hope that it will help improve treatments for various neurological disorders. However, the translational hurdles are high. In this Perspective, we highlight the technical, practical, and regulatory hurdles that lie ahead along the path towards making optogenetic neuromodulation therapies a reality in the clinic.