RT Journal Article
SR Electronic
T1 Pharmacogenomics and Patient Care: One Size Does Not Fit All
JF Science Translational Medicine
FD American Association for the Advancement of Science
SP 153ps18
OP 153ps18
DO 10.1126/scitranslmed.3003471
VO 4
IS 153
A1 Giacomini, Kathleen M.
A1 Yee, Sook Wah
A1 Ratain, Mark J.
A1 Weinshilboum, Richard M.
A1 Kamatani, Naoyuki
A1 Nakamura, Yusuke
YR 2012
UL http://stm.sciencemag.org/content/4/153/153ps18.abstract
AB The time is ripe to assess whether pharmacogenomics research—the study of the genetic basis for variation in drug response—has provided important insights into a personalized approach to prescribing and dosing medications. Here, we describe the status of the field and approaches for addressing some of the open questions in pharmacogenomics research and use of genetic testing in guiding drug therapy.