RT Journal Article SR Electronic T1 Pharmacogenomics and Patient Care: One Size Does Not Fit All JF Science Translational Medicine FD American Association for the Advancement of Science SP 153ps18 OP 153ps18 DO 10.1126/scitranslmed.3003471 VO 4 IS 153 A1 Giacomini, Kathleen M. A1 Yee, Sook Wah A1 Ratain, Mark J. A1 Weinshilboum, Richard M. A1 Kamatani, Naoyuki A1 Nakamura, Yusuke YR 2012 UL http://stm.sciencemag.org/content/4/153/153ps18.abstract AB The time is ripe to assess whether pharmacogenomics research—the study of the genetic basis for variation in drug response—has provided important insights into a personalized approach to prescribing and dosing medications. Here, we describe the status of the field and approaches for addressing some of the open questions in pharmacogenomics research and use of genetic testing in guiding drug therapy.