RT Journal Article
SR Electronic
T1 Evaluating Preclinical Efficacy
JF Science Translational Medicine
FD American Association for the Advancement of Science
SP 96cm22
OP 96cm22
DO 10.1126/scitranslmed.3002757
VO 3
IS 96
A1 Atkinson, Mark A.
YR 2011
UL http://stm.sciencemag.org/content/3/96/96cm22.abstract
AB Recent disappointing results of clinical trials seeking type 1 diabetes (T1D) reversal suggest the need for a reevaluation of our translational efforts. This Commentary explores the need for standards in evaluating therapeutic efficacy in preclinical models of T1D.