PT  - JOURNAL ARTICLE
AU  - Atkinson, Mark A.
TI  - Evaluating Preclinical Efficacy
AID  - 10.1126/scitranslmed.3002757
DP  - 2011 Aug 17
TA  - Science Translational Medicine
PG  - 96cm22--96cm22
VI  - 3
IP  - 96
4099  - http://stm.sciencemag.org/content/3/96/96cm22.short
4100  - http://stm.sciencemag.org/content/3/96/96cm22.full
AB  - Recent disappointing results of clinical trials seeking type 1 diabetes (T1D) reversal suggest the need for a reevaluation of our translational efforts. This Commentary explores the need for standards in evaluating therapeutic efficacy in preclinical models of T1D.