PT - JOURNAL ARTICLE AU - Rappuoli, Rino AU - Medaglini, Donata TI - ADITEC: Joining Forces for Next-Generation Vaccines AID - 10.1126/scitranslmed.3003826 DP - 2012 Apr 04 TA - Science Translational Medicine PG - 128cm4--128cm4 VI - 4 IP - 128 4099 - http://stm.sciencemag.org/content/4/128/128cm4.short 4100 - http://stm.sciencemag.org/content/4/128/128cm4.full AB - Scientists sit poised at a singular moment in the history of vaccine research. Genomics and systems biology have fueled advances in our understanding of human immunology. Together with adjuvant development and structure-based design of immunogens, these next-generation technologies are transforming the field of vaccinology and shaping the future of medicine. However, the sophisticated science behind the development of modern vaccines and the resulting knotty ethical issues have become so complex that scientists and policy-makers need a new model for vaccine research. The European Commission–sponsored Advanced Immunization Technologies project—ADITEC—brings together some of the leading laboratories in the field to tackle the problems that no lab can tackle in isolation.