PT - JOURNAL ARTICLE AU - Lamb, John R. AU - Gibson, Neil W. TI - Complexity in Common Diseases: Big Biology for All AID - 10.1126/scitranslmed.3000882 DP - 2010 Mar 31 TA - Science Translational Medicine PG - 25cm11--25cm11 VI - 2 IP - 25 4099 - http://stm.sciencemag.org/content/2/25/25cm11.short 4100 - http://stm.sciencemag.org/content/2/25/25cm11.full AB - The Commentary of Mills and Sykes in Science Translational Medicine presented their thesis on the advent of high-throughput technologies and the dangers they may represent for the future of biomedical research. In response, we argue that true progress on the diagnosis and treatment of common human diseases will require the advent of big biology and its deep integration with focused research as practiced in both academic and industrial institutions. Copyright © 2010, American Association for the Advancement of Science