RT Journal Article
SR Electronic
T1 Engineered Proteins Pull Double Duty
JF Science Translational Medicine
FD American Association for the Advancement of Science
SP 17ps5
OP 17ps5
DO 10.1126/scitranslmed.3000276
VO 2
IS 17
A1 Cochran, Jennifer R.
YR 2010
UL http://stm.sciencemag.org/content/2/17/17ps5.abstract
AB Myriad bi-specific proteins have been developed that recognize two different clinical targets, with the goal of achieving enhanced therapeutic effects as compared with proteins that interact with only one target. These engineered proteins are starting to enter clinical testing for a variety of biomedical applications, particularly cancer treatment. Copyright © 2010, American Association for the Advancement of Science