PT  - JOURNAL ARTICLE
AU  - Fullerton, Stephanie M.
AU  - Anderson, Nicholas R.
AU  - Guzauskas, Greg
AU  - Freeman, Dena
AU  - Fryer-Edwards, Kelly
TI  - Meeting the Governance Challenges of Next-Generation Biorepository Research
AID  - 10.1126/scitranslmed.3000361
DP  - 2010 Jan 20
TA  - Science Translational Medicine
PG  - 15cm3--15cm3
VI  - 2
IP  - 15
4099  - http://stm.sciencemag.org/content/2/15/15cm3.short
4100  - http://stm.sciencemag.org/content/2/15/15cm3.full
AB  - Advances in clinical translational research have led to an explosion of interest in infrastructure development and data sharing facilitated by biorepositories of specimens and linked health information. These efforts are qualitatively different from the single-center sample collections that preceded them and pose substantial new ethics and regulatory challenges for investigators and institutions. New research governance approaches, which can address current and anticipated challenges, promote high-quality research, and provide a robust basis for ongoing research participation, are urgently required. Copyright © 2010, American Association for the Advancement of Science