Supplementary Materials

The PDF file includes:

  • Materials and Methods
  • Fig. S1. MAP3K2 and MAP3K3 deficiency affects ROS production but not other neutrophil functions.
  • Fig. S2. MAP3K2 and MAP3K3 deficiency reduces ALI phenotypes but not leukocyte infiltration.
  • Fig. S3. MAP3K2/3 regulates NADPH oxidase complex 2 by phosphorylation of p47phox.
  • Fig. S4. p47phox-KI alters pulmonary microenvironments.
  • Fig. S5. p47phox-KI alters pulmonary endothelial microenvironments.
  • Fig. S6. p47phox-KI alters pulmonary epithelial microenvironments.
  • Fig. S7. Pazopanib affects protein phosphorylation and human neutrophils.
  • Fig. S8. Pazopanib ameliorates ALI.
  • Fig. S9. Pazopanib acts through ROS and AKT.
  • Legends for data files S1 and S2

[Download PDF]

Other Supplementary Material for this manuscript includes the following:

  • Data file S1 (Microsoft Excel format). Differentially expressed genes.
  • Data file S2 (Microsoft Excel format). Tabulated raw data.